To provide a scanning suspension comprising a particle having a diameter of at least 1 μm and capable of disturbing a magnetic field at least partly, and the use thereof for obtaining a scanning image.
Preferably, the particle comprises holmium and a composition capable of essentially maintaining its structure during irradiation. The particle is suitable for preparing a kit of parts, comprising a diagnostic composition and a therapeutic composition, both of which comprise the particles with essentially the same chemical structure, wherein the therapeutic composition is more radioactive than the diagnostic composition. The kit of parts is especially suitable for treatment of tumor. Firstly, the distribution of the particles within an individual can be determined with a scanning image obtained with a scanning composition. Subsequently, a radioactive therapeutic composition can be administered, wherein a suitable dose of the therapeutic composition is derived from the scanning image.
VAN HET SCHIP ALFRED DIRK
ZONNENBERG BERNARD ANTONI
UNIV UTRECHT HOLDING BV
JPH07501331A | 1995-02-09 | |||
JPS5976A | 1984-01-05 | |||
JPH05502400A | 1993-04-28 | |||
JP2001327514A | 2001-11-27 | |||
JPH10328319A | 1998-12-15 | |||
JPH0812598A | 1996-01-16 |
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JPN7009003981; Mumper RJ, Ryo UY, Jay M: 'Neutron-activated holmium-166-poly (L-lactic acid) microspheres: a potential agent for the internal' J Nucl Med Vol.32, No.11, 1991, p.2139-43
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Yukitaka Nakamura
Noritaka Yokota
Takeyasu Ito
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