Title:
SCREENING METHOD FOR COGNITION FUNCTION IMPROVING MEDICINE UTILIZING LEARNING CHARACTERISTIC OF BIRD CHICK AFTER INCUBATION
Document Type and Number:
Japanese Patent JP2021001789
Kind Code:
A
Abstract:
To provide a screening method for cognition function improving medicine that can be implemented on a high-order brain function based principally on a frontal association area at extremely low cost and in a short time, and further can be statistically handled.SOLUTION: A screening method includes: the processes of: (1) administering a test substance to a bird chick; (2) implementing a first learning subject on the bird chick to which the test substance has been administered; (3) implementing a second learning subject different from the first learning subject on the bird chick used in the process (2), and a contrast, and then comparing learning effects; and (4) selecting, as a candidate substance, a test substance whose learning effect on the contrast has been acknowledged in the process (3).SELECTED DRAWING: None
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Inventors:
HONMA KOICHI
YAMAGUCHI SHINJI
AOKI NAOYA
YAMAGUCHI SHINJI
AOKI NAOYA
Application Number:
JP2019115147A
Publication Date:
January 07, 2021
Filing Date:
June 21, 2019
Export Citation:
Assignee:
UNIV TEIKYO
International Classes:
G01N33/50; G01N33/15
Domestic Patent References:
| JP2006521115A | 2006-09-21 |
Foreign References:
| US20150018282A1 | 2015-01-15 |
Other References:
YAMAGUCHI, S. ET AL.: "Thyroid hormone determines the start of the sensitive period of imprinting and primes later learning", NATURE COMMUNICATIONS, vol. 3, no. 1081, JPN6023016887, 25 September 2012 (2012-09-25), pages 1 - 13, ISSN: 0005049286
Attorney, Agent or Firm:
Kenjiro Yamaguchi
Hironori Nagayama
Kenichi Morita
Hironori Nagayama
Kenichi Morita