SELECTIVE BROMINATION FOR PARA POSITION OF PHENOL AND PHENOL DERIVATIVES, PHENOL DERIVATIVES BROMINATED IN PARA POSITION AND SOLUTION THEREFOR

Title:

SELECTIVE BROMINATION FOR PARA POSITION OF PHENOL AND PHENOL DERIVATIVES, PHENOL DERIVATIVES BROMINATED IN PARA POSITION AND SOLUTION THEREFOR

Document Type and Number:

Japanese Patent JPS63215643

Kind Code:

A

Abstract:

A highly selective bromination process is described, by means of which substantially pure p-bromophenols can be obtained, by brominating a phenol derivative, for example a compound of the formula: wherein R1 is hydrogen, alkyl, aryl, alkyl aryl or heteroaryl group; and R2, R3 and R4 each independently represents hydrogen, alkyl alkoxy, aryl, hydroxy, methylenedioxy, amino, acylamide or halogen or two R2, R3 and R4 together form a naphthalenic residue. The process is carried out by reacting with bromine or bromine chloride in an ester as the solvent, at temperatures comprised between about -20 DEG C and about +50 DEG C. Bromination solutions useful for carrying out this process are also disclosed.

Inventors:

ABURAMU BETSUKAA
NURITSUTO KOONBERUGU
BERUTA KUROITORU

Application Number:

JP32003887A

Publication Date:

September 08, 1988

Filing Date:

December 16, 1987

Export Citation:

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Assignee:

BROMINE COMPOUNDS LTD

International Classes:

C07B31/00; C07B39/00; C07C27/00; C07C37/62; C07C39/27; C07C41/00; C07C41/22; C07C43/225; C07C67/00; C07D317/62; (IPC1-7): C07B39/00; C07C37/62; C07C39/27; C07C43/225; C07D317/62

Attorney, Agent or Firm:

Nishikyo Keiichiro (1 outside)

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