Title:
3-(Z)-プロペニルセフェム化合物の選択的な製造方法
Document Type and Number:
Japanese Patent JP4018546
Kind Code:
B2
Abstract:
A 3-(Z)-propenyl cephem compound is selectively prepared by reacting a phosphoranylidene cephem compound with acetaldehyde in the presence of a base in a solvent mixture comprising diethyl ether, formula (I), wherein R is a carboxyl protecting group; R1 is hydrogen or R2CH2CO-; and R2 is ethyl, 2-thiophenyl, phenyl, p-hydroxyphenyl or phenoxy
Inventors:
Lee, Gwang-Sun
Chang, Yun-Kill
Kim, Hong-Sun
Lee, Jae Hong
Park, Chulu-Hyun
Park, gassun
Kim, Chul-Kyun
Chang, Yun-Kill
Kim, Hong-Sun
Lee, Jae Hong
Park, Chulu-Hyun
Park, gassun
Kim, Chul-Kyun
Application Number:
JP2002581447A
Publication Date:
December 05, 2007
Filing Date:
April 17, 2002
Export Citation:
Assignee:
Hammi Farm. Seeo., LDT.
International Classes:
C07D501/22; A61K31/545; A61P31/04; C07D501/00; C07D501/04
Domestic Patent References:
| JP62000491A |
Attorney, Agent or Firm:
Takehiko Suzue
Satoshi Kono
Makoto Nakamura
Kurata Masatoshi
Takashi Mine
Yoshihiro Fukuhara
Sadao Muramatsu
Ryo Hashimoto
Satoshi Kono
Makoto Nakamura
Kurata Masatoshi
Takashi Mine
Yoshihiro Fukuhara
Sadao Muramatsu
Ryo Hashimoto