Title:
SEMEN PLASMIN* ITS MANUFACTURE AND BACTERICIDE* FUNGICIDE* ANTITUMOR OR RNAASYNTHESISSSUPPRESSING AGENT CONTAINING SAME
Document Type and Number:
Japanese Patent JPS55167227
Kind Code:
A
Abstract:
Seminal plasmin is a protein which has a sedimentation coefficient of 1.04 S in the ultracentrifuge, an isoelectric point of 9.8, and has no methionine as amino-acid component, and can be obtained by removing the spermatozoa from mammalian sperm, dialysing the resulting plasma against a buffer solution of pH 5 to 9, treating the dialysed plasma with an anion exchanger and then with a cation exchanger, eluting the adsorbed protein from the cation exchanger with a buffer solution and finally purifying the resulting product by biochemical methods known per se, using the inhibition of growth of E. coli as test system for the purification. It is suitable as bactericidal, fungicidal or antitumour agent or for inhibiting RNA synthesis.
Inventors:
PUSHIYUPA MITORA BARUGABUA
ERUGAMU RETSUDEI SHIYAMU PURAS
KAARU HAINTSU SHIYAITO
ERUGAMU RETSUDEI SHIYAMU PURAS
KAARU HAINTSU SHIYAITO
Application Number:
JP3767180A
Publication Date:
December 26, 1980
Filing Date:
March 26, 1980
Export Citation:
Assignee:
MAX PLANCK GESELLSCHAFT
COUNCIL SCIENT IND RES
COUNCIL SCIENT IND RES
International Classes:
C12N9/68; A61K35/52; A61K38/16; A61P3/00; A61P31/04; A61P35/00; (IPC1-7): A61K37/54; C12N9/68