Title:
HSP90阻害剤に対する感受性
Document Type and Number:
Japanese Patent JP2012500013
Kind Code:
A
Abstract:
The present invention relates to a combination of cell lines as well as a method of selecting (a) cell(s), (a) tissue(s) or (a) cell culture(s) with susceptibility to an HSP90 inhibitor anti-tumor agent. Also a method for determining the responsiveness of a mammalian tumor cell or cancer cell or collection of cells or cell lines to treatment with a drug such as an HSP90 inhibitor anti-tumor agent is described herein.
Inventors:
Roman, thomas
Marling, catherine
Zander, Thomas
From malt, Peter
Wong, Kioku-Kin
Marling, catherine
Zander, Thomas
From malt, Peter
Wong, Kioku-Kin
Application Number:
JP2011523410A
Publication Date:
January 05, 2012
Filing Date:
August 17, 2009
Export Citation:
Assignee:
Max-Plank-Gezelle Shaft Tool Verderungk Del Wissenschafften A. Fau.
Universitts Cologne
Universitts Cologne
International Classes:
C12Q1/04; A61K31/395; A61K31/5377; A61P35/00; C12N5/07; C12Q1/68; G01N33/15; G01N33/48; G01N33/50; C07D225/06; C07D261/18; C12N15/09
Other References:
JPN6014003506; ＰＬｏＳ ＯＮＥ ｖｏｌ．３ ｎｏ．３ ｅ１７２２, 200803, ｐｐ．１-８
JPN6014003507; Ａｎｎ Ｔｈｏｒａｃ Ｓｕｒｇ ｖｏｌ．７０, 2000, ｐｐ．１８５３-１８６０
JPN6014003509; Ｃｌｉｎ Ｃａｎｃｅｒ Ｒｅｓ ｖｏｌ．１３ ｎｏ．１０, 2007, ｐｐ．２８９０-２８９６
JPN6014003510; ＰｌｏＳ Ｍｅｄｉｃｉｎｅ ｖｏｌ．２ ｎｏ．１ ｅ１７, 2005, ｐｐ．００５７-００６１
JPN6014003511; Ｃａｎｃｅｒ Ｒｅｓ ｖｏｌ．６７ ｎｏ．１０, 2007, ｐｐ．４９３３-４９３９
JPN6014003513; Ｃａｎｃｅｒ Ｒｅｓ ｖｏｌ．６８ ｎｏ．１４, 200807, ｐｐ．５８２７-５８３８
JPN6014003507; Ａｎｎ Ｔｈｏｒａｃ Ｓｕｒｇ ｖｏｌ．７０, 2000, ｐｐ．１８５３-１８６０
JPN6014003509; Ｃｌｉｎ Ｃａｎｃｅｒ Ｒｅｓ ｖｏｌ．１３ ｎｏ．１０, 2007, ｐｐ．２８９０-２８９６
JPN6014003510; ＰｌｏＳ Ｍｅｄｉｃｉｎｅ ｖｏｌ．２ ｎｏ．１ ｅ１７, 2005, ｐｐ．００５７-００６１
JPN6014003511; Ｃａｎｃｅｒ Ｒｅｓ ｖｏｌ．６７ ｎｏ．１０, 2007, ｐｐ．４９３３-４９３９
JPN6014003513; Ｃａｎｃｅｒ Ｒｅｓ ｖｏｌ．６８ ｎｏ．１４, 200807, ｐｐ．５８２７-５８３８
Attorney, Agent or Firm:
Hiroshi Kobayashi
Eiji Katayama
Norio Omori
Yasuhito Suzuki
Eiji Katayama
Norio Omori
Yasuhito Suzuki