Title:
SEPARATION OF STEREOISOMERIC VINYLCYCLOPROPANE CARBOXYLIC ACID
Document Type and Number:
Japanese Patent JPS54100350
Kind Code:
A
Abstract:
A process for the separation of the cis- and trans-stereoisomers of a substituted vinylcyclopropanecarboxylic acid of the formula in which R is alkyl with 1 to 4 carbon atoms, halogen, phenyl or phenyl substituted by at least one of alkyl and halogen, and R1 is hydrogen, alkyl with 1 to 4 carbon atoms or halogen, or R and R1, together with the adjacent C atom, form a carbocyclic ring, comprising reacting the free vinylcyclopropanecarboxylic acid in a weakly alkaline aqueous solution with an amount of an amine salt corresponding to the proportion of the cis-isomer present thereby to form a salt precipitate enriched in one of the stereoisomers, separating the precipitant from the supernatant, separately reacting the precipitate and supernatant with a strong acid to liberate the isomeric vinylcyclopropanecarboxylic acid, and recrystallizing at least one of the stereoisomers.
Inventors:
KURAUSU NAUMAN
Application Number:
JP34479A
Publication Date:
August 08, 1979
Filing Date:
January 08, 1979
Export Citation:
Assignee:
BAYER AG
International Classes:
C07C51/00; C07C51/42; C07C51/487; C07C61/35; C07C61/16; C07C61/39; C07C61/40; C07C67/00; (IPC1-7): C07C51/42; C07C61/18; C07C61/28