Title:
逐次的抗癌治療
Document Type and Number:
Japanese Patent JP7156949
Kind Code:
B2
Abstract:
Human clinical use of a chimeric poliovirus construct has demonstrated excellent anti-tumor effect. Sequential treatment with the virus construct followed by chemotherapy drugs increases the anti-tumor effect. Tumors of different types are susceptible to the combination treatment, including but not limited to melanoma, glioblastoma, renal cell carcinoma, prostate cancer, breast cancer, lung cancer, medulloblastoma, and colorectal cancer.
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Inventors:
Bigner Darrell Dee.
Gromeyer Massayas
Desjardins Annick
Friedman Henry S.
Friedman Alan H.
Sampson John H.
Gromeyer Massayas
Desjardins Annick
Friedman Henry S.
Friedman Alan H.
Sampson John H.
Application Number:
JP2018549578A
Publication Date:
October 19, 2022
Filing Date:
March 20, 2017
Export Citation:
Assignee:
Duke University
International Classes:
A61K35/76; A61K31/175; A61K31/4188; A61K39/395; A61P35/00; A61P43/00
Other References:
Oncogene,2008年,Vol.27,pp.264-273
脳外誌,2015年,Vol.24,No.6,pp.386-398
Oncolytic virotherapy,2016年1月6日,Vol.5,pp.1-13
Molecular Therapy,2010年,Vol.18,No.2,pp.251-263
Molecular Therapy,2013年,Vol.21,No.6,pp.1212-1223
脳外誌,2015年,Vol.24,No.6,pp.386-398
Oncolytic virotherapy,2016年1月6日,Vol.5,pp.1-13
Molecular Therapy,2010年,Vol.18,No.2,pp.251-263
Molecular Therapy,2013年,Vol.21,No.6,pp.1212-1223
Attorney, Agent or Firm:
Shimizu Hatsushi
Masao Haruna
Hirotaka Yamaguchi
Shun Jinbe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Hideki Kodera
Masato Ozeki
Kazuya Kawamoto
Masao Haruna
Hirotaka Yamaguchi
Shun Jinbe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Hideki Kodera
Masato Ozeki
Kazuya Kawamoto