Title:
セリンプロテアーゼインヒビター
Document Type and Number:
Japanese Patent JP4452017
Kind Code:
B2
Abstract:
Compounds of formula (I) where R5, R6a, each X, L, Cy and Lp are as defined in the specification, are tryptase inhibitors useful as antiinflammatory agents.
Inventors:
Sarah Elizabeth Lively
Martin James Harrison
Neil Jason Naylor
Christopher Neil Farthing
Bourdan Waskowitz
Martin James Harrison
Neil Jason Naylor
Christopher Neil Farthing
Bourdan Waskowitz
Application Number:
JP2002549329A
Publication Date:
April 21, 2010
Filing Date:
December 12, 2001
Export Citation:
Assignee:
TULARIK LIMITED
International Classes:
C07D277/20; C07D333/66; A61K31/381; A61K31/4025; A61K31/4155; A61K31/426; A61K31/427; A61K31/428; A61K31/4365; A61K31/4436; A61K31/4535; A61K31/496; A61K31/5377; A61P1/04; A61P7/02; A61P9/10; A61P11/06; A61P17/00; A61P17/06; A61P19/02; A61P25/00; A61P27/02; A61P29/00; A61P37/08; A61P43/00; C07C237/42; C07D209/08; C07D211/34; C07D211/46; C07D211/60; C07D213/56; C07D213/61; C07D213/73; C07D233/54; C07D273/00; C07D277/30; C07D277/40; C07D277/46; C07D277/52; C07D277/60; C07D277/68; C07D277/82; C07D307/54; C07D307/79; C07D333/36; C07D333/60; C07D333/68; C07D333/78; C07D333/80; C07D401/12; C07D409/04; C07D409/06; C07D409/12; C07D417/12; C07D495/04
Domestic Patent References:
| JP2002510448A |
Foreign References:
| WO1999055661A1 | ||||
| WO1999011658A1 |
Other References:
DORMAN, D. E., et al.,Isolation and Structure Elucidation of the Major Degradation Products of Cefaclor in the Solid State,Journal of Pharmaceutical Sciences,1997年,86(5),p. 540-549
MOSES, P., et al.,Hydrogenation studies of α-oximino and α-phenylhydrazono phenylacetamides,Arkiv foer Kemi,1964年,22(33),p. 451-467
AL-OBAID, A. M., et al.,Synthesis and biological evaluation of new cyclopenteno[b]thiophene derivatives as local anesthetic and antiarrhythmic agents,Pharmazie,1998年,53(1),p. 24-28
MOSES, P., et al.,Hydrogenation studies of α-oximino and α-phenylhydrazono phenylacetamides,Arkiv foer Kemi,1964年,22(33),p. 451-467
AL-OBAID, A. M., et al.,Synthesis and biological evaluation of new cyclopenteno[b]thiophene derivatives as local anesthetic and antiarrhythmic agents,Pharmazie,1998年,53(1),p. 24-28
Attorney, Agent or Firm:
Mitsuo Tanaka
Minato Saito
Minato Saito