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Title:
SESQUITERPENE-BASED COMPOUND
Document Type and Number:
Japanese Patent JPH09278708
Kind Code:
A
Abstract:

To obtain a sesquiterpene-based compound useful as a raw material for a medicine, especially an antibacterial agent or an antifungal agent.

This sesquiterpene-based compound is shown by formula I (R is H, ammonium, an alkali metal or a lower alkyl) or formula II. The compound is obtained by finely cutting the fruit body of Roseofomes subflexibilis Aoshi as a mushroom of the family Polyporaceae, immersing the fruit body in acetone, ethyl acetate or a lower alcohol at room temperature for 1-3 days to give an extracted essence, concentrating the essence under reduced pressured suspending a viscous residue in water, extracting the suspension with ethyl acetate and purifying the extract by silica gel chromatography, preparative thin-layer chromatography, high-performance liquid chromatography, etc.


Inventors:
NOZOE SHIGEO
TAKAHASHI AKIRA
MASUDA JUNICHI
TANAKA KENICHI
TANAKA SANAE
KANO MUNEAKI
SEGAWA TOSHIAKI
Application Number:
JP11698596A
Publication Date:
October 28, 1997
Filing Date:
April 15, 1996
Export Citation:
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Assignee:
TOAGOSEI CO LTD
International Classes:
C07D307/92; A61K31/19; A61K31/365; A61K36/07; A61P31/04; A61P31/10; C07C62/36; C07C69/757; (IPC1-7): C07C62/36; C07C69/757; C07D307/92