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Title:
【発明の名称】アルキルおよびアリールアラニンP2部分を含むC型肝炎ウイルスに対する大員環NS3-セリンプロテアーゼ阻害剤
Document Type and Number:
Japanese Patent JP2003531199
Kind Code:
A
Abstract:
The present invention discloses novel macrocyclic compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such macrocycles as well as methods of using them to treat disorders associated with the HCV protease.

Inventors:
Slicant Benkatraman
Kevin X Chen
Ashok Arasapan
F. George Nujologue
Bjjor M Girijabaraban
Tin-Yau Chang
Brian A. McTrick
Andrew Jay Prongay
Vincent S. Madison
Application Number:
JP2001578418A
Publication Date:
October 21, 2003
Filing Date:
April 17, 2001
Export Citation:
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Assignee:
SCHERING CORPORATION
International Classes:
A61K31/7052; A61K38/00; A61K38/08; A61K38/21; A61P31/12; A61P31/14; A61P43/00; A61K45/00; C07D273/00; C07K5/02; C07K7/02; C07K7/64; (IPC1-7): C07K7/64; A61K31/7052; A61K38/00; A61K38/21; A61K45/00; A61P31/12; A61P43/00
Foreign References:
WO1999064442A11999-12-16
Other References:
JPN5002028668, MARCHETTI A, SYNLETT, 199906, N S01, P1000−1002, DE, THIEME VERLAG
Attorney, Agent or Firm:
Aoyama Ryo (2 outside people)