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Title:
SlpA AS TOOL FOR RECOMBINANT PROTEIN AND ENZYME TECHNOLOGY
Document Type and Number:
Japanese Patent JP2009284902
Kind Code:
A
Abstract:

To provide a recombinant DNA molecule encoding a fusion protein comprising an SlpA chaperone and a target polypeptide, a corresponding expression vector encoding the fusion protein and a host cell transformed with the expression vector.

Provided are a recombinantly produced fusion protein comprising an SlpA chaperone and a target polypeptide, and the use of the recombinantly produced fusion protein as a binding partner in immunoassay or a means for reducing interference.


Inventors:
FAATZ ELKE DR
SCHAARSCHMIDT PETER
URBAN SCHMITT
SCHOLZ CHRISTIAN
Application Number:
JP2009124803A
Publication Date:
December 10, 2009
Filing Date:
May 25, 2009
Export Citation:
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Assignee:
HOFFMANN LA ROCHE
International Classes:
C12N15/09; A61K39/00; A61P19/02; A61P25/28; A61P29/00; A61P31/04; A61P31/12; C07K19/00; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N9/90; C12P21/02; G01N33/53; G01N33/531; G01N33/543
Foreign References:
WO2007077008A12007-07-12
Other References:
JPN6013027354; Sci. Rept., Fac. Agr.,Meijo Univ. Vol.36, 2000, pp.57-66
JPN6013027357; J. Bacteriol. Vol.176, No.7, 1994, pp.2068-2081
JPN6013027347; J. Mol. Biol. Vol.345, No.5, 2005, pp.1229-1241
JPN6013027351; J. Biol. Chem. Vol.272, No.25, 1997, pp.15697-15701
JPN6013027354; Sci. Rept., Fac. Agr.,Meijo Univ. Vol.36, 2000, pp.57-66
JPN6013027357; J. Bacteriol. Vol.176, No.7, 1994, pp.2068-2081
Attorney, Agent or Firm:
Yusuke Hiraki
Ishii Teiji
Satoshi Fujita
Eiichi Arai
Natsuo Tanaka