Title:
Ａ型インフルエンザＲＮＡ依存性ＲＮＡポリメラーゼの低分子阻害剤
Document Type and Number:
Japanese Patent JP6415568
Kind Code:
B2
Abstract:
Antiviral compositions and methods are contemplated that are especially effective in the treatment and prevention of influenza A viruses. Also presented are cellular assays to identify small molecule compounds having antiviral properties, particularly as it relates to detection of influenza A RNA-dependent RNA polymerase activity in a mammalian cell independent of other influenza A components. Preferred assays allow for identification of viral replication inhibitors that do not disrupt normal cellular activity.
Inventors:
Niazi, Cayvan
La Visa Day, Charlus
Lenny, Ann-Laura
Buzco, Oleksandr
Golovat, Justin
Sun-Sion, Patrick
La Visa Day, Charlus
Lenny, Ann-Laura
Buzco, Oleksandr
Golovat, Justin
Sun-Sion, Patrick
Application Number:
JP2016539125A
Publication Date:
October 31, 2018
Filing Date:
December 11, 2013
Export Citation:
Assignee:
Nantes Holdings IP, LRC
International Classes:
A61K31/519; A61P31/16; A61P43/00; C07D471/04
Domestic Patent References:
| JP5070353A | ||||
| JP2008531656A |
Foreign References:
| WO2007076055A1 |
Attorney, Agent or Firm:
Ryoichi Takaoka
Nao Oda
Akiyo Iwahori
Kaoru Takahashi
Nao Oda
Akiyo Iwahori
Kaoru Takahashi
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