Title:
SMOOTH MUSCLE CELL CONSTRUCTS
Document Type and Number:
Japanese Patent JP2016028575
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide methods of reconstruction, augmentation or replacement of luminal organs or tissue structures in a subject in need by using scaffolds seeded with cells obtained from sources that are not derived from the corresponding organ or tissue structure that is the subject of the reconstruction, augmentation or replacement.SOLUTION: An implantable cell-scaffold construct for treating a subject in need comprises: a) a scaffold comprising a matrix having a first surface, where the matrix is shaped to conform to at least a part of a native luminal organ or tissue structure in the subject; and b) a first cell population derived from a source that is non-autologous to the subject and is not the native organ or tissue structure deposited on or in the first surface, the scaffold and the first cell population forming an implantable construct.SELECTED DRAWING: None
Inventors:
JOHN W LUDLOW
MANUEL J JAYO
JOYDEEP BASU
TIMOTHY A BERTRAM
CHRISTOPHER W GENHEIMER
KELLY I GUTHRIE
ILAGAN ROGER M
DEEPAK JAIN
OLUWATOYIN A KNIGHT
RICHARD PAYNE
SARAH F QUINLAN
H SCOTT RAPOPORT
NAMRATA D SANGHA
JACOB E SHOKES
TERESA B BURNETTE
SARAH A BOYD
CRAIG R HALBERSTADT
DOMINIC M JUSTEWICZ
ELIAS A RIVERA
WENDY SHARP
MANUEL J JAYO
JOYDEEP BASU
TIMOTHY A BERTRAM
CHRISTOPHER W GENHEIMER
KELLY I GUTHRIE
ILAGAN ROGER M
DEEPAK JAIN
OLUWATOYIN A KNIGHT
RICHARD PAYNE
SARAH F QUINLAN
H SCOTT RAPOPORT
NAMRATA D SANGHA
JACOB E SHOKES
TERESA B BURNETTE
SARAH A BOYD
CRAIG R HALBERSTADT
DOMINIC M JUSTEWICZ
ELIAS A RIVERA
WENDY SHARP
Application Number:
JP2015159431A
Publication Date:
March 03, 2016
Filing Date:
August 12, 2015
Export Citation:
Assignee:
TENGION INC
International Classes:
C12N5/07; A61L27/00; C12N5/00
Attorney, Agent or Firm:
Sonoda Yoshitaka
Kobayashi Yoshinori
Kobayashi Yoshinori