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Patent Searching and Data


Title:
SOFT GELATIN CAPSULE AND ITS PREPARATION
Document Type and Number:
Japanese Patent JPH07149625
Kind Code:
A
Abstract:
PURPOSE: To produce a soft gelatin capsule without causing a change in composition of a capsule filling and deformation, etc., of the capsule. CONSTITUTION: This liquid-filled soft gelatin capsule contains a mobile ingredient (other than glycerol) present even in a capsule filling in a capsule shell prepared from gelatin, a plasticizer and, as desired, further an auxiliary material. The mobile ingredient is a pharmaceutically acceptable nonvolatile solvent mixable with the gelatin or capable of forming a solid solution with the gelatin. Tetrahydrofuryl alcohol ether, diethylene glycol monoethyl ether, polyethylene glycol and propylene glycol are cited and 1,2-propylene glycol is especially preferred. The content thereof in the capsule shell is 5-40%, preferably 10-32%. Problems of tack caused when formulating the 1,2-propylene glycol are solved by carrying out the cooling of a gelatin band at the time of production with a cooling drum cooled with a liquid cooling medium.

Inventors:
BUERUNAA BUROTSUKUSU
ARUMIN MAINTSUAA
HORUSUTO TSUANDE
Application Number:
JP23110794A
Publication Date:
June 13, 1995
Filing Date:
September 27, 1994
Export Citation:
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Assignee:
SCHERER GMBH R P (DE)
SANDOZ AG
International Classes:
A61J3/07; A61K9/107; A61K9/48; A61K9/50; A61K9/52; A61K9/56; A61K9/64; A61K9/66; A61K31/436; A61K31/7048; A61K31/7052; A61K38/13; A61P31/04; A61P37/06; B65B9/04; A61K38/00; (IPC1-7): A61K9/48; A61J3/07
Attorney, Agent or Firm:
Aoyama Ryo (1 person outside)