Title:
SOLID FORM OF THE MAGNESIUM SALT OF (S)-OMEPRAZOLE AND METHOD FOR MANUFACTURING THE SAME
Document Type and Number:
Japanese Patent JP2014169302
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide a novel solid form of the magnesium salt of (S)-omeprazole and a method for manufacturing the same.SOLUTION: The provided method for manufacturing a novel solid form comprises: a) a step of crystallizing an S-omeprazole magnesium salt from an S-omeprazole magnesium salt solution within a solvent system including a methanol/water mixture including at least 0.01 mL of water with respect to 1 g of an S-omeprazole magnesium salt starting material; b) a step of separating the S-omeprazole magnesium salt emerging at the previous step; and c) a step of separating a free organic solvent from the obtained S-omeprazole magnesium salt.
Inventors:
RAMON BERENGUER MAIMO
LAURA COPPI
GUILLEN YOLANDA GASANZ
JORGE MEDRANO RUPEREZ
LAURA COPPI
GUILLEN YOLANDA GASANZ
JORGE MEDRANO RUPEREZ
Application Number:
JP2014088458A
Publication Date:
September 18, 2014
Filing Date:
April 22, 2014
Export Citation:
Assignee:
ESTEVE QUIMICA SA
International Classes:
C07D401/12; A61K31/4439; A61P1/04
Domestic Patent References:
JP5575366B2 | 2014-08-20 | |||
JP2004002422A | 2004-01-08 | |||
JP2002501529A | 2002-01-15 | |||
JP2002114779A | 2002-04-16 | |||
JPH08512315A | 1996-12-24 | |||
JP2000509067A | 2000-07-18 | |||
JP2001507025A | 2001-05-29 | |||
JP2003507475A | 2003-02-25 | |||
JPH09502739A | 1997-03-18 |
Foreign References:
US6312712B1 | 2001-11-06 | |||
WO2004046134A2 | 2004-06-03 | |||
WO2002085889A1 | 2002-10-31 | |||
WO2004020436A1 | 2004-03-11 |
Other References:
社団法人 日本化学会, 第4版 実験化学講座 基本操作I, JPN6011026736, 1990, pages 184 - 186, ISSN: 0003064391
浅原 照三, 溶剤ハンドブック, JPN6011026738, 1985, pages 47 - 51, ISSN: 0003064392
浅原 照三, 溶剤ハンドブック, JPN6011026738, 1985, pages 47 - 51, ISSN: 0003064392
Attorney, Agent or Firm:
Yoshitaka Sonoda
Yoshinori Kobayashi
Yoshinori Kobayashi
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