SOLID FORMS OF BERBERINE URSODEOXYCHOLATE, AND COMPOSITIONS AND METHODS THEREOF

Title:

SOLID FORMS OF BERBERINE URSODEOXYCHOLATE, AND COMPOSITIONS AND METHODS THEREOF

Document Type and Number:

Japanese Patent JP2023104925

Kind Code:

A

Abstract:

To provide novel solid forms (e.g., crystalline forms) of berberine ursodeoxycholate (BBR-UDCA) having one or more desirable properties, such as high stability, high crystallinity, high purity, low hygroscopicity, favorable dissolution properties and/or favorable mechanical properties.SOLUTION: There is provided a solid form, which is Form A of BBR-UDCA, having an X-ray powder diffraction (XRPD) pattern comprising one or more peaks at 2θ values selected from the group consisting of specific values obtained using Cu Kα radiation (λ1=1.540598 Å, λ2=1.544426 Å, intensity ratio λ2/λ1=0.50).SELECTED DRAWING: Figure 1

Inventors:

YU MENG
LIU LIPING
FU XINXIANG

Application Number:

JP2023020228A

Publication Date:

July 28, 2023

Filing Date:

February 13, 2023

Export Citation:

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Assignee:

SHENZHEN HIGHTIDE BIOPHARMACEUTICAL LTD

International Classes:

C07D455/03; C07J9/00

Attorney, Agent or Firm:

Kiyohara International Patent Office

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