Title:
固相担体、リガンド結合固相担体、標的物質の検出又は分離方法、及び前記固相担体の製造方法
Document Type and Number:
Japanese Patent JP6618916
Kind Code:
B2
Abstract:
Provided is a solid phase carrier which has high water dispersibility, allows facilitated binding of a ligand to a reactive functional group, and exhibits suppressed non-specific adsorption, and with which, in the case of using the solid phase carrier by having a ligand bound thereto, for example, detection of a target substance can be carried out with high sensitivity and low noise. Disclosed is a solid phase carrier having bound thereto a polymer including a structural unit represented by the following Formula (1) and a structural unit represented by the following Formula (2):
wherein in Formula (1),
R 1 represents a hydrogen atom or a methyl group; and
R 2 represents an organic group having a zwitterionic structure,
in Formula (2),
R 3 represents a hydrogen atom or a methyl group
R 4 represents -(C=O)-O-*, -(C=O)-NR 6 -* (wherein R 6 represents a hydrogen atom or a methyl group; and the symbol * represents a position of bonding to R 5 in Formula (2)), or a phenylene group;
in a case in which R 4 represents -(C=O)-O-*, R 5 represents a hydrogen atom, or an organic group having a reactive functional group, and in a case in which R 4 represents -(C=O)-NR 6 -* or a phenylene group, R 5 represents an organic group having a reactive functional group,
provided that R 5 is not an organic group having a zwitterionic structure.
Inventors:
Ueya Yuichi
Application Number:
JP2016547430A
Publication Date:
December 11, 2019
Filing Date:
September 07, 2015
Export Citation:
Assignee:
JSR CORPORATION
JSR Life Science Co., Ltd.
JSR Life Science Co., Ltd.
International Classes:
G01N33/543
Domestic Patent References:
| JP2009542862A |
Foreign References:
| WO2013047527A1 |
Other References:
北野博巳,源明誠,生体適合性と水和,高分子,日本,高分子学会,2009年 2月,Vol.58 / No.2,pp.74-77
Attorney, Agent or Firm:
Alga Patent Office, a patent business corporation
Toshio Takano
Toshio Nakajima
Masaki Murata
Hiroto Yamamoto
Toshio Takano
Toshio Nakajima
Masaki Murata
Hiroto Yamamoto