Title:
SOLID PREPARATIONS
Document Type and Number:
Japanese Patent JP2015221781
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide layering particles in which bitterness of ibuprofen and incompatibility with other components are suppressed, and dissolution properties of ibuprofen are improved, in layering particles containing ibuprofen and a component which causes incompatibility with ibuprofen.SOLUTION: Layering particles in which quick dissolution properties of ibuprofen are ensured without impairing storage stability and ingestibility can be obtained by coating water-soluble nuclear particles with a layer (internal layer) containing ibuprofen and a swollen type disintegrator, and further coating the internal layer with a layer (outer layer) containing a disintegrator.
Inventors:
ONO TETSUHISA
SUZUKI KYOKO
ABE SHIGEKI
SUZUKI KYOKO
ABE SHIGEKI
Application Number:
JP2015089764A
Publication Date:
December 10, 2015
Filing Date:
April 24, 2015
Export Citation:
Assignee:
TAISHO PHARMACEUTICAL CO LTD
International Classes:
A61K31/192; A61K9/20; A61K47/26; A61K47/32; A61K47/36; A61K47/38; A61P29/00
Domestic Patent References:
| JP2001055322A | 2001-02-27 | |||
| JPH04273816A | 1992-09-30 | |||
| JP2009520704A | 2009-05-28 | |||
| JP2006016329A | 2006-01-19 | |||
| JP2008037863A | 2008-02-21 |
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