SOLUBILIZER FOR FAT-SOLUBLE P-HYDROXYBENZOIC ACID AND THE LIKE, SOLUTION AND APPLICATION

Title:

SOLUBILIZER FOR FAT-SOLUBLE P-HYDROXYBENZOIC ACID AND THE LIKE, SOLUTION AND APPLICATION

Document Type and Number:

Japanese Patent JP2003252799

Kind Code:

A

Abstract:

To provide a solubilizer solubilizing p-hydroxybenzoic acid and the like having ≥1.0 distribution coefficient of octanol/water without using a solvent such as an alcohol.

The solubilizer for fat-soluble p-hydroxybenzoic acid and the like comprises an aqueous solution containing a 2- methacryloyloxyethylphosphorylcholine/buthyl methacrylate copolymer, the solubilizer comprises an aqueous solution containing 1-5 wt.% 2- methacryloyloxyethylphosphorylcholine/buthyl methacrylate copolymer, the solubilizer solubilizing 0.01-0.4 wt.% fat-soluble p-hydroxybenzoic acid and the like based on whole solubilizing agent is provided, a solution of a fat-soluble p-hydroxybenzoic acid and the like, obtained by using the solubilizer is provided and the application of the solution as an antiseptic is provided.

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Inventors:

SUGIBAYASHI KENJI
KIN MOTOYASU
TSUCHIDA MAMORU

Application Number:

JP2002057910A

Publication Date:

September 10, 2003

Filing Date:

March 04, 2002

Export Citation:

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Assignee:

NOF CORP

International Classes:

A61K47/12; A61K8/30; A61K8/33; A61K8/72; A61K8/81; A61K9/08; A61K47/32; C08K3/20; C08L33/14; C08L43/02; (IPC1-7): A61K47/12; A61K7/00; A61K9/08; A61K47/32; C08K3/20; C08L33/14; C08L43/02

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