SOLUBLE CELLULOSE DERIVATIVE, ITS PRODUCTION, GRAFT CELLULOSE, AND BIOCOMPATIBLE MATERIAL

Title:

SOLUBLE CELLULOSE DERIVATIVE, ITS PRODUCTION, GRAFT CELLULOSE, AND BIOCOMPATIBLE MATERIAL

Document Type and Number:

Japanese Patent JPH10212301

Kind Code:

A

Abstract:

To obtain a biocompatible material having high durability and biocompatibility by grafting a free-radical-polymerizable monomer onto a soluble cellulose deriv. having peroxyester groups bonded in a homogeneous system.

This soluble cellulose driv. is obtd. by reacting a halogenated peroxyester compd. (e.g. t-butyl peroxy-2-bromoacetate) with a soluble cellulose (e.g. methylcellulose having a degree of substitution of 1.6-2.2) in the presence of a basic compd. (e.g. lithium hydride) and is represented by the formula (where R1 is H, methyl, ethyl, hydroxyethyl, etc.; R2 is a 1-15C divalent hydrocarbon group; R3 is a 4-15C monovalent hydrocarbon group; and (m) is 0.001-1). An example of the free-radical-polymerizable monomer is 2-(meth) acryloyloxyethyl-2-(trimethylammonio)ethyl phosphate. The reaction is conduted at -10°C to 10°C for 4-48hr.

Inventors:

FUKUI HIROKI
MATSUYAMA KAZUO
ISHIHARA KAZUHIKO
NAKABAYASHI NORIO

Application Number:

JP1498897A

Publication Date:

August 11, 1998

Filing Date:

January 29, 1997

Export Citation:

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Assignee:

NOF CORP
NAKABAYASHI NORIO
ISHIHARA KAZUHIKO
KAGAKU GIJUTSU SHINKO JIGYODAN

International Classes:

A61L27/00; C08B3/22; C08B15/02; C08F251/02; (IPC1-7): C08B15/02; A61L27/00; C08B3/22; C08F251/02

Attorney, Agent or Firm:

Sakai Hajime

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