SPECIFIC GLUCOCORTICOSTEROID COMPOUND HAVING ANTI-INFLAMMATORY ACTIVITY

Title:

SPECIFIC GLUCOCORTICOSTEROID COMPOUND HAVING ANTI-INFLAMMATORY ACTIVITY

Document Type and Number:

Japanese Patent JP2011093929

Kind Code:

A

Abstract:

To provide a new compound which is an androstane-type glucocorticoid receptor agonist.

The compound is expressed by formula (I) (in the formula, X is O or S; R1 is 1-6C alkyl, 3-8C cycloalkyl, 3-8C cycloalkylmethyl, 3-8C cycloalkenyl or the like; R2 is hydrogen, methyl or methylene; and R3 and R4 are each independently hydrogen, halogen or methyl).

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Inventors:

BIGGADIKE KEITH
JOHN MATTHEW PETER
NEEDHAM DEBORAH

Application Number:

JP2011001699A

Publication Date:

May 12, 2011

Filing Date:

January 07, 2011

Export Citation:

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Assignee:

GLAXO GROUP LTD

International Classes:

C07J31/00; A61P5/44; C07D215/26; C07D233/54; C07D233/60; C07D451/02; C07J1/00; C07J3/00; A61K31/569; A61P11/02; A61P11/06; A61P29/00; A61P37/00

Foreign References:

WO2003035668A2	2003-05-01
WO2002012266A1	2002-02-14
WO2002088167A1	2002-11-07

Other References:

JPN6010050137; ＰＨＩＬＬＩＰＰＳ，Ｇ．Ｈ．　ｅｔ　ａｌ．: Ｊ．　Ｍｅｄ．　Ｃｈｅｍ．Ｖｏｌ．３７，　Ｎｏ．２２, 1994, ｐ．３７１７-２９
JPN6013000246; ＳＴＯＵＣＨ，Ｔ．Ｒ．　ｅｔ　ａｌ．: Ｊ．　Ｍｅｄ．　Ｃｈｅｍ．Ｖｏｌ．２９，　Ｎｏ．１１, 1986, ｐ．２１２５-３６

Attorney, Agent or Firm:

Yusuke Hiraki
Ishii Teiji
Satoshi Fujita

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