Title:
IL-17調節剤としてのスピロ環インドリン
Document Type and Number:
Japanese Patent JP7163379
Kind Code:
B2
Abstract:
A series of substituted spirocyclic 2-oxoindoline derivatives, and analogues thereof, being potent modulators of human IL-17 activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including inflammatory and autoimmune disorders.
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Inventors:
Brace, Gareth Neal
Chappell, Rose Elizabeth
Debove, Hervé Jean-Claude
Foley, Anne-Marie
Folkes, Gregory
Jones, Elizabeth Pearl
Lecomte, Fabian Claude
Quincy, Joanna Rachel
Schultz, Monica - Sarah Elizabeth Dorothea
Selby, Matthew Duncan
Smalley, Adam Peter
Taylor, Richard David
Townsend, Robert James
Zoo, Jaonin
Chappell, Rose Elizabeth
Debove, Hervé Jean-Claude
Foley, Anne-Marie
Folkes, Gregory
Jones, Elizabeth Pearl
Lecomte, Fabian Claude
Quincy, Joanna Rachel
Schultz, Monica - Sarah Elizabeth Dorothea
Selby, Matthew Duncan
Smalley, Adam Peter
Taylor, Richard David
Townsend, Robert James
Zoo, Jaonin
Application Number:
JP2020519841A
Publication Date:
October 31, 2022
Filing Date:
June 12, 2018
Export Citation:
Assignee:
UCB Biopharma SRL
International Classes:
C07D471/10; A61K31/407; A61K31/41; A61K31/4155; A61K31/416; A61K31/4178; A61K31/4184; A61K31/4192; A61K31/4196; A61K31/422; A61K31/423; A61K31/4245; A61K31/426; A61K31/428; A61K31/433; A61K31/437; A61K31/438; A61K31/4433; A61K31/496; A61K31/497; A61K31/4985; A61K31/501; A61K31/506; A61K31/52; A61K31/5377; A61K31/541; A61K45/00; A61P29/00; A61P37/06; A61P43/00; C07D487/10; C07D491/107; C07D491/20; C07D495/10; C07D519/00
Domestic Patent References:
JP1250352A | ||||
JP60246386A | ||||
JP57102863A | ||||
JP2015529673A | ||||
JP2007526879A | ||||
JP2015508086A | ||||
JP2015514762A |
Foreign References:
US4835280 | ||||
US4810801 | ||||
WO2008057280A1 | ||||
CN1502608A | ||||
WO2015169962A1 |
Other References:
Bioorganic & Medicinal Chemistry Letters,2017年,27(1),P.109-113
Attorney, Agent or Firm:
Patent Attorney Corporation Asamura Patent Office
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