Title:
AMPKモジュレーターとして有用なスピロインドール-シクロプロパンインドリノン
Document Type and Number:
Japanese Patent JP2013513569
Kind Code:
A
Abstract:
The present invention relates to a compound of formula (I) as well as pharmaceutically acceptable salt thereof, wherein R1 to R4 have the significance given in claim 1. The compound may be used, for example, for the treatment or prophylaxis of obesity, hyperglycemia, dyslipidemia, and type 1 or type 2 diabetes.
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Inventors:
Chen
Feng, Lee Chun
Ho, Yun
Fan, menway
Yun, Hong Yin
Feng, Lee Chun
Ho, Yun
Fan, menway
Yun, Hong Yin
Application Number:
JP2012542526A
Publication Date:
April 22, 2013
Filing Date:
December 08, 2010
Export Citation:
Assignee:
F. HOFFMANN-LA ROCHE AKTIENGESELLSCHAFT
International Classes:
C07D209/96; A61K31/404; A61K31/4155; A61K31/4178; A61K31/422; A61K31/4439; A61K31/454; A61K31/496; A61K31/5377; A61P3/04; A61P3/06; A61P3/10; A61P43/00; C07D401/04; C07D401/06; C07D401/12; C07D403/04; C07D403/06; C07D403/10; C07D403/12; C07D405/06; C07D413/10; C07D413/12; C07D491/107
Domestic Patent References:
| JP2008509216A | 2008-03-27 | |||
| JP2007502844A | 2007-02-15 |
Foreign References:
| WO2010115279A1 | 2010-10-14 | |||
| WO2004037247A1 | 2004-05-06 | |||
| WO2007008664A1 | 2007-01-18 |
Other References:
JPN6014040625; Ｂｉｏｏｒｇａｎｉｃ ＆ Ｍｅｄｉｃｉｎａｌ Ｃｈｅｍｉｓｔｒｙ Ｌｅｔｔｅｒｓ １６（８）, 2006, ２１０９-２１１２
Attorney, Agent or Firm:
Patent business corporation Tsukuni
Hajime Tsukuni
Yasuo Yanagibashi
Satoko Ito
Keiko Ozawa
Toshio Miyake
Yasuhiro Oguni
Yoko Tanaka
Atsushi Shiomi
Fusayuki Saito
Hajime Tsukuni
Yasuo Yanagibashi
Satoko Ito
Keiko Ozawa
Toshio Miyake
Yasuhiro Oguni
Yoko Tanaka
Atsushi Shiomi
Fusayuki Saito