Title:
トリプターゼ阻害剤として使用するためのスピロピペリジン
Document Type and Number:
Japanese Patent JP2011504499
Kind Code:
A
Abstract:
The present invention is directed to a compound of Formula (I): or a form thereof, wherein X1, X2, X3, X4, R1, R2 and R3 are as defined herein, useful as tryptase inhibitors.
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Inventors:
Costanzo, Michael Jei
Yabutu, Stephen Sea
Townzie, bullet
Marianov, Bruce Yee
Twang, Han-Chiang
Yabutu, Stephen Sea
Townzie, bullet
Marianov, Bruce Yee
Twang, Han-Chiang
Application Number:
JP2010534955A
Publication Date:
February 10, 2011
Filing Date:
November 19, 2008
Export Citation:
Assignee:
JANSSEN PHARMACEUTICA NAAMLOZE VENNOOTSCHAP
International Classes:
C07D405/06; A61K31/438; A61K31/444; A61K31/506; A61K31/675; A61P1/04; A61P1/16; A61P9/00; A61P9/10; A61P11/00; A61P11/02; A61P11/06; A61P13/12; A61P17/00; A61P17/04; A61P17/06; A61P19/02; A61P19/04; A61P19/06; A61P27/02; A61P29/00; A61P35/00; A61P37/08; A61P43/00; C07D471/10; C07D491/107; C07D495/10; C07D519/00; C07F9/6561
Domestic Patent References:
| JP2004532838A | 2004-10-28 | |||
| JP2007526264A | 2007-09-13 | |||
| JP2007530580A | 2007-11-01 | |||
| JP2004510697A | 2004-04-08 | |||
| JP2003531193A | 2003-10-21 | |||
| JP2006522132A | 2006-09-28 |
Foreign References:
| WO2007002114A1 | 2007-01-04 |
Other References:
JPN7013003161; ＣＡｐｌｕｓ（ＳＴＮ） ＡＮ ２００８：４５１４７６
JPN6013041814; Ｂｉｏｏｒｇａｎｉｃ ＆ Ｍｅｄｉｃｉｎａｌ Ｃｈｅｍｉｓｔｒｙ Ｌｅｔｔｅｒｓ １８, 20080130, ２１１４-２１２１
JPN6013041814; Ｂｉｏｏｒｇａｎｉｃ ＆ Ｍｅｄｉｃｉｎａｌ Ｃｈｅｍｉｓｔｒｙ Ｌｅｔｔｅｒｓ １８, 20080130, ２１１４-２１２１
Attorney, Agent or Firm:
Patent business corporation Odashima patent office