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Title:
SQUAMOUS EPITHELIAL CANCER CELL GROWTH INHIBITOR
Document Type and Number:
Japanese Patent JP2009149615
Kind Code:
A
Abstract:

To provide a squamous epithelial cancer chemotherapeutic agent having low toxicity, carcinogenicity, and teratogenicity.

A squamous epithelial cancer cell growth inhibitor characterized by comprising 50-500 g/mL of a glyceride mixture of -linolenic acid triglyceride with -linolenic acid diglyceride, and -linolenic acid monoglyceride is provided.


Inventors:
REIMUTA SHUICHI
NAKAJIMA TOSHIAKI
SASAKI HIROMI
AOYAGI KAZUHIKO
Application Number:
JP2008296535A
Publication Date:
July 09, 2009
Filing Date:
November 20, 2008
Export Citation:
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Assignee:
IDEMITSU KOSAN CO
NAT CANCER CT JAPAN
International Classes:
A61K31/232; A61P35/00; A61P43/00
Domestic Patent References:
JP2005194222A2005-07-21
JP2000336029A2000-12-05
JP2006342074A2006-12-21
JP2005198648A2005-07-28
JP2005179211A2005-07-07
JPH07233062A1995-09-05
JPH07126160A1995-05-16
JPH0347119A1991-02-28
JPS5791915A1982-06-08
JP2009096799A2009-05-07
JP2006347984A2006-12-28
JP2005194222A2005-07-21
JP2000336029A2000-12-05
JP2006342074A2006-12-21
JP2005198648A2005-07-28
JP2005179211A2005-07-07
JPH07233062A1995-09-05
JPH07126160A1995-05-16
JPH0347119A1991-02-28
JPS5791915A1982-06-08
JP2009096799A2009-05-07
Other References:
JPN6013029602; JOUBERT,A.M. et al: 'Comparative study of the effects of polyunsaturated fatty acids and their metabolites on cell growth' Prostaglandins, Leukotrienes and Essential Fatty Acids Vol.61, No.3, 1999, p.171-182
JPN6013029606; FERGUSON,P.J.: 'Cytotoxic and chemomodulative effects of gamma-linolenic acid (GLA) against a human squamous carcino' Proceedings of the American Association for Cancer Research Annual Meeting Vol.36, 1995, p.290
JPN6013029608; TAKEDA,S. et al: 'CYTOTOXIC EFFECTS OF POLYUNSATURATED FATTY ACIDS AGAINST HUMAN ORAL CANCER CELL LINES' FASEB Journal Vol.3, No.3, 1989, p.A471
Attorney, Agent or Firm:
Yoshiyuki Kawaguchi
Hidemi Matsukura
Tsutomu Toyama
Shinichi Sanuki
Takeshi Niwa
Tomoko Tsujida