Title:
STABILIZATION OF AQUEOUS HYALURONIC ACID SOLUTION
Document Type and Number:
Japanese Patent JPH01113401
Kind Code:
A
Abstract:
PURPOSE:To inhibit a gradual decrease of the viscosity of an aqueous hyaluronic acid solution with time thereby making it possible to improve the long-term storage stability thereof, by adding a phenolic compound to an aqueous solution of hyaluronic acid or a salt thereof. CONSTITUTION:A phenolic compound is added to an aqueous solution of hyaluronic acid or a salt thereof. Said phenolic compound means a compound which has at least one phenol skeleton in the molecule and, for example, phenol, pyrogallol, vanillin and tannin can be mentioned. To add the phenolic compound to the aqueous solution of hyaluronic acid or a salt thereof means that the above compound is dissolved or dispersed in the aqueous solution and it is preferred that the concentration is 0.0001wt.% or more.
Inventors:
MIYAMORI TAKAO
NUMAZAWA RYOZO
SAKIMAE AKIHIRO
ONISHI HISAO
NUMAZAWA RYOZO
SAKIMAE AKIHIRO
ONISHI HISAO
Application Number:
JP27138187A
Publication Date:
May 02, 1989
Filing Date:
October 27, 1987
Export Citation:
Assignee:
MITSUBISHI RAYON CO
International Classes:
C08B37/08; (IPC1-7): C08B37/08