Stabilization of tiotropium solvent Japanese food

Title:

Stabilization of tiotropium solvent Japanese food

Document Type and Number:

Japanese Patent JP6158939

Kind Code:

B2

Abstract:

A method for stabilization of micronized or milled solvates of tiotropium bromide, in which the solvates are deposited in a saturated atmosphere of the adequate solvent for the time period sufficient for recovery of the original amount of solvent in the solvate. A stable tiotropium bromide solvate with 1,3-propanediol.

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Inventors:

Igor Cerna
Josef Hiaychek
Ond Jay Dummel
Moccar Kebbatty
Pascal billot
Patrick Jose

Application Number:

JP2015541008A

Publication Date:

July 05, 2017

Filing Date:

November 05, 2012

Export Citation:

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Assignee:

Zentiva, Car.S.

International Classes:

C07D451/10; A61K31/46; A61P11/00; A61P11/06

Domestic Patent References:

JP2008540366A
JP2008540367A

Foreign References:

WO2010101538A2

Attorney, Agent or Firm:

Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Yoichi Watanabe
Masaru Nakajima
Ryotaro Takei

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