Title:
STABLE TAUROLIDINE ELECTROLYTE SOLUTION
Document Type and Number:
Japanese Patent JP2010059166
Kind Code:
A
Abstract:
To provide a taurolidine solution with a higher stability without requiring a specific storage adjustment and solving problems in stability of conventional high concentration taurolidine solutions.
The substantially isotonic about 1.5-3 wt.% taurolidine aqueous solution includes stability increasing amounts of NaCl, KCl, CaCl2, NaHCO3 and their mixture, about 1-10 wt.% of PVP having about 1,000-15,000 average molecular wt. and in addition, about 0.3-1 wt.% of taurine.
Inventors:
PFIRRMANN ROLF W
Application Number:
JP2009243908A
Publication Date:
March 18, 2010
Filing Date:
October 22, 2009
Export Citation:
Assignee:
GEISTLICH SOEHNE AG
International Classes:
A61K31/549; A61K9/08; A61K31/185; A61K31/54; A61K33/14; A61K47/02; A61K47/18; A61K47/20; A61K47/32; A61P7/08; C07D285/08
Domestic Patent References:
| JPS6372626A | 1988-04-02 | |||
| JPS60105618A | 1985-06-11 | |||
| JPH05505615A | 1993-08-19 | |||
| JP2000300661A | 2000-10-31 | |||
| JP2001010976A | 2001-01-16 | |||
| JPH045242A | 1992-01-09 | |||
| JPH04300838A | 1992-10-23 | |||
| JP2000516196A | 2000-12-05 |
Attorney, Agent or Firm:
Michiharu Soga
Hidetoshi Furukawa
Suzuki Kenchi
Kajinami order
Kazuhiro Oyaku
Hidetoshi Furukawa
Suzuki Kenchi
Kajinami order
Kazuhiro Oyaku