Title:
立体選択的開環反応
Document Type and Number:
Japanese Patent JP4010562
Kind Code:
B2
Abstract:
The present invention relates a process for stereoselective or regioselective chemical synthesis which generally comprises reacting a nucleophile and a chiral or prochiral cyclic substrate in the presence of a non-racemic chiral catalyst to produce a steroisomerically or regioselectively enriched product.
Inventors:
Jakobsen, Eritsk N
Layton, Ames El
Martinez, Louis Yi
Layton, Ames El
Martinez, Louis Yi
Application Number:
JP52781796A
Publication Date:
November 21, 2007
Filing Date:
March 14, 1996
Export Citation:
Assignee:
AVANT IMMUNOTHERAPEUTICS,INC.
International Classes:
B01J31/22; C07B53/00; C07B57/00; C07B61/00; C07C213/02; C07C247/02; C07C247/14; C07C251/24; C07D207/12; C07D317/36; C07F7/08; C07F7/10; C07F7/18
Domestic Patent References:
| JP5202022A | ||||
| JP6065159A | ||||
| JP6509981A |
Other References:
NUGENT W. A., Chiral Lewis Acid Catalysis. Enatioselective Addition of Azide to Meso Epoxides, J. Am. Chem. Soc., 1992年, 114(7), p.2768-2769
BONHOTE P., 137. Asymmetric Catalysis by Vitamin B12. The Mechanism of the Cob(I)alamin-Catalyzed Isomerization of 1,2-Epoxycyclpentane to (R)-Cyclopent-2-enol, Helveica Chimica Acta, 1991年, 74, p.1425-1444
LARROW J. F. et al., J. Org. Chem., 1994年, 59(7), p.1939-1942
HAYASHI M. et al., J. Chem. Soc., Chem. Commun., 1994年, p.2699-2700
YAMASHITA H. and MUKAIYAMA T., Chemistry Letters, 1985年, p.1643-1646
YAMASHITA H., Bull. Chem. Soc. Jpn., 1988年, 61(4), p.1213-1220
BONHOTE P., 137. Asymmetric Catalysis by Vitamin B12. The Mechanism of the Cob(I)alamin-Catalyzed Isomerization of 1,2-Epoxycyclpentane to (R)-Cyclopent-2-enol, Helveica Chimica Acta, 1991年, 74, p.1425-1444
LARROW J. F. et al., J. Org. Chem., 1994年, 59(7), p.1939-1942
HAYASHI M. et al., J. Chem. Soc., Chem. Commun., 1994年, p.2699-2700
YAMASHITA H. and MUKAIYAMA T., Chemistry Letters, 1985年, p.1643-1646
YAMASHITA H., Bull. Chem. Soc. Jpn., 1988年, 61(4), p.1213-1220
Attorney, Agent or Firm:
Heikichi Odashima