PURPOSE: To provide a system capable of synthetically sterilizing pathogenic microbes by adding not only an agent or a vaccine but also physical or electrical effects thereto.

CONSTITUTION: This sterilization system is obtained by orally administering an aluminum agent, a zinc agent or an iodine pharmaceutical preparation, further providing a bypass in a lymphatic duct or a blood vessel and extracorporeally circulating a humor therethrough. The front and rear ends of a pipe for the extracorporeal circulation comprise a readily handleable polymer and the intermediate part comprises the pipe of a three- or a four-layer structure. In the case of the three-layer structure, the outer layer comprises an insulator such as a polymer and the middle layer comprises a conductor such as silver, copper, gold or aluminum. The inner layer comprises a semiconductor such as alumina, zinc oxide or barium titanate. In the case of the pipe of the four-layer structure, a metallic oxide, etc., hardly conducting electricity, etc., are further formed as a thin layer on the inside and the electricity is made to flow through the conductor so as not to destroy spherical cells. Furthermore, diluted iodine or a hormone containing the iodine such as L-triiodithyronine or a water- soluble substance of Paramecium caudatum, a thyroid-stimulating hormone or acetylcholine, etc., are contained in a liquid such as a saline solution and injected into a position of the polymer on this side of the conductor or semiconductor.