STEROID COMPOUND DERIVATIVES REACTED WITH CELL POISONOUS SUBSTANCE

Title:

STEROID COMPOUND DERIVATIVES REACTED WITH CELL POISONOUS SUBSTANCE

Document Type and Number:

Japanese Patent JPS5982399

Kind Code:

A

Abstract:

The present application is concerned with compounds useful as carriers of cytotoxic agents. More particularly it deals with derivatives of steroid compounds having a 5-androstene carbon skeleton and having an oleyl ester at the 3-position and having a 17-carbamyl alkyl substituent which linked to cytotoxic agents for delivery to cancer cells exclusively via the low-density lipoprotein (LDL) pathway.

More Like This:

JP5386362	Use of pregnane and androstane steroids for the manufacture of pharmaceutical compositions for the treatment of CNS diseases
JPH1072352	INFECTION SOLUTION OF PREDNISOLONE SODIUM METHYL SUCCINATE
WO/2003/051388	PHARMACEUTICAL COMPOSITION OF INTERFERON GAMMA OR PIRFENIDONE WITH MOLECULAR DIAGNOSTICS FOR THE IMPROVED TREATMENT OF INTERSTITIAL LUNG DISEASES

Inventors:

REIMONDO EE FUAIASUTOON

Application Number:

JP18178083A

Publication Date:

May 12, 1984

Filing Date:

September 29, 1983

Export Citation:

Click for automatic bibliography generation Help

Assignee:

MERCK & CO INC

International Classes:

A61K31/57; A61K31/575; A61P35/00; A61P43/00; C07J9/00; C07J41/00; C07J43/00; (IPC1-7): A61K31/57; A61K31/575; C07J41/00; C07J43/00

Attorney, Agent or Firm:

Masao Okabe

Previous Patent: Heat type air flow rate sensor

Next Patent: MANUFACTURE OF EPOXYSTEROID USING NONCYCLIC AMINE