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Patent Searching and Data


Title:
STEROID DERIVATIVE
Document Type and Number:
Japanese Patent JPH07228593
Kind Code:
A
Abstract:

PURPOSE: To obtain a new compound useful as an antibacterial or anti- inflammatory agent.

CONSTITUTION: This new compound as a steroid derivative has the structure expressed by formula I (R is H, methyl or OH), where the carboxyl group of a quinolonecarboxylic acid and the 21-site alcoholic hydroxyl group of a steroid compound are linked to each other by esterification {e.g. 11β,17,21- trihydroxy-4-piperazinyl)-4-oxo-3-quinolinecarboxylatel }. The compound of formula I is obtained by reaction between a quinolonecarboxylic acid of formula II and a steroid-21-halogen of formula III (X is a halogen).


Inventors:
Ogata, Kazumi
Sakagami, Yukihiro
Isowaki, Yuuichi
Nakao, Hidetoshi
Ito, Kazuhiko
Application Number:
JP1994000302585
Publication Date:
August 29, 1995
Filing Date:
December 07, 1994
Export Citation:
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Assignee:
SENJU PHARMACEUT CO LTD
International Classes:
A61K31/58; A61P29/00; A61P31/04; C07J43/00; (IPC1-7): C07J43/00; A61K31/58