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Title:
STEROID SULFATASE INHIBITOR
Document Type and Number:
Japanese Patent JP2003238413
Kind Code:
A
Abstract:

To provide a steroid sulfatase inhibitor containing a thiophosphate derivative or its pharmacologically permissible salt as an active component.

The steroid sulfatase inhibitor contains a thiophosphate derivative of formula (I) (R1 and R2 are each independently H or a substituted or unsubstituted lower alkyl; and O-R3 is a monocyclic alcohol residue or a polycyclic alcohol residue) or its pharmacologically permissible salt as an active component. For example, the active component is a thiophosphate derivative of formula I wherein R1 and R2 are each hydrogen atom and R3 is a group of formula A or a pharmacologically permissible salt of the derivative.


Inventors:
AMISHIRO NOBUYOSHI
MURAMATSU KOZUE
MURAGATA TSUTOMU
Application Number:
JP2002036372A
Publication Date:
August 27, 2003
Filing Date:
February 14, 2002
Export Citation:
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Assignee:
KYOWA HAKKO KOGYO KK
International Classes:
A61K31/661; A61P5/24; A61P35/00; A61P43/00; C07J1/00; C07J41/00; C07J43/00; (IPC1-7): A61K31/661; A61P5/24; A61P35/00; A61P43/00