Title:
ストレプトアビジン突然変異タンパク質およびそれらを使用する方法
Document Type and Number:
Japanese Patent JP7094565
Kind Code:
B2
Abstract:
The invention concerns novel streptavidin muteins and methods of determining, immobilizing, isolating or purifying proteins under denaturing conditions. In one embodiment such a mutein has an Cys residue at sequence position 127 of the wild-type sequence of streptavidin and comprises at least one mutation in the region of the amino acid positions 117 to 121 with reference to the amino acid sequence of wild type streptavidin.
Inventors:
Schmidt Thomas
Application Number:
JP2019506543A
Publication Date:
July 04, 2022
Filing Date:
April 25, 2017
Export Citation:
Assignee:
Eveer Life Sciences Gem Beher
International Classes:
C12N15/31; C07K1/22; C07K14/36; C07K17/00; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/63; C12P21/02
Domestic Patent References:
| JP2015535006A |
Foreign References:
| WO2013017954A2 | ||||
| WO1997011183A1 |
Other References:
Nat. Biotechnol., 1996, Vol.14, pp.1007-1011
Attorney, Agent or Firm:
Shimizu Hatsushi
Masao Haruna
Hirotaka Yamaguchi
Shun Jinbe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Hideki Kodera
Masato Ozeki
Kazuya Kawamoto
Masao Haruna
Hirotaka Yamaguchi
Shun Jinbe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Hideki Kodera
Masato Ozeki
Kazuya Kawamoto