Title:
STREPTOGRAMINS UNDER REFINING STATE, ITS PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING IT
Document Type and Number:
Japanese Patent JPH06298664
Kind Code:
A
Abstract:
PURPOSE: To obtain a streptogramins useful as pharmaceuticals having antibacterial activity. CONSTITUTION: One or more kinds of streptogramins represented by formula I [A1 is a group represented by formula II (R' is H or hydroxyl and Y is H, methylamino or dimethylamino), etc., R is ethyl, etc., and each of R1 and R2 is H, etc.] are combined and cocrystallized with one or more kinds of streptogramins represented by formula III (R" is H, methyl or ethyl) at a weight ratio of 10:90 to 90:10 to obtain the objective streptogramins, which are then purified in the form of a coprecipitate or fine powder. The resultant streptogramins are used as an antibacterial agent and also used for purifying the streptogramins represented by the formula III.
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Inventors:
ANGER PASCAL (FR)
BONNAVAUD BERTRAND (FR)
CALLET ALAIN (FR)
LEFEVRE PATRICK (FR)
BONNAVAUD BERTRAND (FR)
CALLET ALAIN (FR)
LEFEVRE PATRICK (FR)
Application Number:
JP4057994A
Publication Date:
October 25, 1994
Filing Date:
February 16, 1994
Export Citation:
Assignee:
RHONE POULENC RORE SA
International Classes:
A61P31/04; C07K1/14; C07K5/06; C07K5/078; C07K7/06; C07K14/195; A61K38/00; C07K14/41; C12P17/18; (IPC1-7): A61K37/02; C07K1/14; C07K7/06
Attorney, Agent or Firm:
Heiyoshi Odashima
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