To provide a stress, resistance and tolerance protein encoding Corynebacterium glutamicum gene used for the discrimination of microorganism for the production of fine chemicals, control of the production of fine chemicals by bacteria, classification or discrimination of bacteria, use as a reference point for the preparation of a genom map and as a label for genetic transformation.
The invention provides an isolated nucleic acid molecule or a designated SRT nucleic acid molecule encoding a new SRT protein derived from Corynebacterium glutamicum. The invention also provides its antisense nucleic acid molecule, a recombinant expression vector containing SRT nucleic acid molecule, and host cell into which the expression vector is to be introduced. The invention still further provides isolated SRT protein, mutated SRT protein, fusion protein, antigenic peptide and method for the improvement of the production of a desired compound from C. glutamicum based on genetic engineering of SRT genes of this organism.
COPYRIGHT: (C)2007,JPO&INPIT
KROEGER BURKHARD
SCHROEDER HARTWIG
ZELDER OSKAR
HABERHAUER GREGOR
LEE HEUNG-SHICK
KIM HYUNG-JOON