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Title:
SUBSTANCE FO-2047 AND ITS PRODUCTION
Document Type and Number:
Japanese Patent JPH08127583
Kind Code:
A
Abstract:

PURPOSE: To obtain the subject new substance, having active oxygen scavenging actions and useful for diseases in which free radicals are regarded as participating to, e.g. various inflammations, disorder after ischemia-reperfusion, aging of skin, etc.

CONSTITUTION: This substance FO-2047 is a compound of the formula. The substance FO-2047 has the following physicochemical properties: property: white powder; molecular weight: 215.0938 (measured by a high-resolution electron ionization mass spectrometry); molecular formula: C13H13NO2; melting point: 147-152°C; specific rotatory power: [α]25D=-10.2 (c=0.6, ethanol); solubility: soluble in MeOH, EtOH and CHCl3 and sparingly soluble in water; color reaction: positive to ninhydrin, sulfuric acid and iodine; weakly basic, etc. The compound of the formula is obtained by aerobically culturing a microorganism belonging to the genus Penicillium which is preferably Penicillium sp. FO-2047 (FERM P-14530) and collecting the substance from the resultant culture medium.


Inventors:
OMURA SATOSHI
SHIOMI KAZURO
KOMIYAMA HIROKI
MASUMA ROKUROU
Application Number:
JP1994000266566
Publication Date:
May 21, 1996
Filing Date:
October 31, 1994
Export Citation:
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Assignee:
KITASATO INST
International Classes:
C12P17/18; A61K31/40; A61P9/08; A61P9/10; A61P17/00; A61P29/00; C07D487/04; C12N1/14; C12R1/80; (IPC1-7): C07D487/04; C12N1/14; C12P17/18
Attorney, Agent or Firm:
小林 和憲