SUBSTANCE HAVING ANTITUMOR ACTIVITY

Title:

SUBSTANCE HAVING ANTITUMOR ACTIVITY

Document Type and Number:

Japanese Patent JPH01191694

Kind Code:

A

Abstract:

NEW MATERIAL:A substance SATS 2542 having an antitumor activity and the following physicochemical properties and produced by an microorganism belonging to the genus Alteromonas. Decomposition point: decomposes at 213W245°C into a brown color; specific rotation: [α]20D=+25°(c=0.02, water); an aqueous solution of 1.0mg/ml is weekly acidic W neutral: solubility:soluble in water and slightly soluble or insoluble in organic solvents such as alcohols. acetone, ethyl ether, hexane, chloroform and ethyl acetate, mol. wt.:≥100,000 (gel filtration method); coloring reaction: positive to biuret reaction. Folin's reaction, anthrone sulfuric acid reaction and cysteine sulfuric acid reaction and negative to ninhydrin reaction, etc.

USE: An antitumor agent.

PREPARATION: Alteromonas sp.SCRC-2542 (FERM P-9819) is cultured.

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Inventors:

SAKAI KUNIKAZU
YAMADA KAORU
ISHII YOSHIMITSU
YAZAWA KAZUYOSHI
ARAKI KEIKO
KONDO SEI

Application Number:

JP1575488A

Publication Date:

August 01, 1989

Filing Date:

January 28, 1988

Export Citation:

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Assignee:

SAGAMI CHEM RES

International Classes:

C12N1/20; A61K35/74; A61K38/00; A61P35/00; C07K14/00; C07K14/005; C07K14/195; C07K14/41; C12P21/00; C12R1/01; (IPC1-7): A61K35/74; A61K37/02; C07K15/04; C07K15/14; C12N1/20; C12P21/00

Attorney, Agent or Firm:

Aoki Akira (4 outside)

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