SUBSTANCE-INTRODUCING AGENT AND PRODUCTION METHOD THEREOF

Title:

SUBSTANCE-INTRODUCING AGENT AND PRODUCTION METHOD THEREOF

Document Type and Number:

Japanese Patent JP2005139140

Kind Code:

A

Abstract:

To provide a substance-introducing agent which efficiently introduces an objective substance and has no cytotoxic activity induced by an infectious virus itself.

The objective substance (e.g. a natural or synthetic substance such as a nucleic acid, a peptide, a protein, polysaccharides, glycolipid and a physiologically active substance) is encapsulated in a liposome (an active genosome) having a viral coat protein on its surface. The active genosome enables effective introduction of the objective substance into a target cell.

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Inventors:

KAWAI AKIHIKO

Application Number:

JP2003379189A

Publication Date:

June 02, 2005

Filing Date:

November 07, 2003

Export Citation:

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Assignee:

KANSAI TLO KK

International Classes:

C12N15/09; A61K9/127; A61K38/00; A61K47/18; A61K47/24; A61K47/26; A61K47/28; A61K48/00; A61P3/06; A61P7/00; A61P9/00; A61P19/04; A61P21/04; A61P25/00; A61P25/14; A61P35/00; C07K14/005; (IPC1-7): A61K9/127; A61K38/00; A61K47/18; A61K47/24; A61K47/26; A61K47/28; A61K48/00; A61P3/06; A61P7/00; A61P9/00; A61P19/04; A61P21/04; A61P25/00; A61P25/14; A61P35/00

Domestic Patent References:

JPH11187873A	1999-07-13
JPH10505320A	1998-05-26
JP2003512306A	2003-04-02
JPH02124830A	1990-05-14

Attorney, Agent or Firm:

Eiji Saegusa
Kakehi Yuro
Takeshi Ohara
Kenji Saito
Jun Fujii
Hitoshi Seki
Mutsuko Nakano

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