Title:
SUBSTANCE FOR USE IN DIETARY SUPPLEMENTATION OR FOR PREPARATION OF MEDICAMENT FOR TREATMENT OF NON-INSULIN DEPENDENT DIABETES MELLITUS, HYPERTENSION AND/OR METABOLIC SYNDROME
Document Type and Number:
Japanese Patent JP2012153721
Kind Code:
A
Abstract:
To provide a substance for the preparation of a medicament of non-insulin dependent diabetes mellitus, hypertension and/or metabolic syndrome.
The substance includes the chemical structures of bicyclo[3.2.1]octane or the chemical structures of kaurene for the use in a dietary supplementation or as a constituent in a medicament for the treatment of non-insulin dependent diabetes mellitus, hypertension and/or the metabolic syndrome. The unique chemical structures of bicyclo[3.2.1]octane alone or in a kaurene structure provides the substances, such as e.g. steviol, isosteviol and stevioside with the capability of enhancing or potentiating the secretion of insulin in a plasma glucose dependent manner.
Inventors:
HERMANSEN KJELD
GREGERSEN SOEREN
BENDIX-JEPPESEN PER
GREGERSEN SOEREN
BENDIX-JEPPESEN PER
Application Number:
JP2012112329A
Publication Date:
August 16, 2012
Filing Date:
May 16, 2012
Export Citation:
Assignee:
STEVIA APS
International Classes:
A61K31/19; A23L1/30; A61K38/00; A61K31/015; A61K31/045; A61K31/352; A61K31/7034; A61K31/704; A61K36/00; A61K36/28; A61K36/48; A61K45/06; A61P3/00; A61P3/04; A61P3/06; A61P3/10; A61P5/50; A61P9/12; C07C13/64; C07C13/68; C07C61/35; C07H15/24; C07H15/256
Domestic Patent References:
| JPH06157302A | 1994-06-03 | |||
| JP2002500677A | 2002-01-08 |
Other References:
JPN6011021571; Ｄｉａｂｅｔｏｌｏｇｉａ Ｖｏｌ． ３９， Ｎｏ． ＳＵＰＰＬ． １, 1996, ｐｐ． Ａ１２５．
JPN6011021572; Ｃｅｌｌ Ｓｉｇｎａｌｌｉｎｇ １０，１０, 1998, ７２７-７３３
JPN6011021572; Ｃｅｌｌ Ｓｉｇｎａｌｌｉｎｇ １０，１０, 1998, ７２７-７３３
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita
Previous Patent: PYRAZOLE KINASE MODULATOR AND METHOD OF USE
Next Patent: PHOSPHORAMIDATE ALKYLATOR PRODRUG
Next Patent: PHOSPHORAMIDATE ALKYLATOR PRODRUG