Title:
置換ピペラジン
Document Type and Number:
Japanese Patent JP4988355
Kind Code:
B2
Abstract:
Compounds are provided that act as potent antagonists of the CCR1 receptor, and have in vivo anti-inflammatory activity. The compounds are generally aryl piperazine derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR1-mediated diseases, and as controls in assays for the identification of competitive CCR1 antagonists.
Inventors:
Pennell Andrew M. K.
Agen James Bee.
Light jay jay kim
Sen Subhabrata
McMaster Brian E.
Deari daniel joseph
Chain way
Chan Penri
Agen James Bee.
Light jay jay kim
Sen Subhabrata
McMaster Brian E.
Deari daniel joseph
Chain way
Chan Penri
Application Number:
JP2006544042A
Publication Date:
August 01, 2012
Filing Date:
December 08, 2004
Export Citation:
Assignee:
Chemocentrics Incorporated
International Classes:
C07D401/04; A61K31/496; A61K31/506; A61P1/00; A61P9/00; A61P11/06; A61P17/00; A61P17/04; A61P17/06; A61P19/00; A61P19/02; A61P25/00; A61P25/16; A61P25/28; A61P29/00; A61P37/02; A61P37/08; A61P43/00; C07D231/12; C07D231/16; C07D231/18; C07D231/38; C07D231/56; C07D401/12; C07D401/14; C07D403/04; C07D403/14; C07D405/04; C07D409/04; C07D413/04; C07D413/14; A61K31/497; A61K31/501; A61K31/52; A61K31/53; A61K31/5377; A61K31/541; C07D231/14; C07D231/20; C07D233/60; C07D235/06; C07D249/08; C07D249/14; C07D257/04; C07D403/06; C07D403/12; C07D413/12; C07D417/04; C07D471/04; C07D473/36
Domestic Patent References:
| JP11513364A | ||||
| JP4257570A | ||||
| JP2006508036A | ||||
| JP62292782A | ||||
| JP58052256A |
Foreign References:
| WO2002014314A1 | ||||
| WO2003051841A1 | ||||
| WO2004035556A1 | ||||
| WO2004013130A1 | ||||
| WO2003053366A1 | ||||
| WO2003008395A1 |
Other References:
J. Med. Chem.,2001年,vol.44, no.16,p.2601-2611
Attorney, Agent or Firm:
Hatsushi Shimizu
Koichi Niimi
Koichi Niimi