Title:
女性のヘルスケアにおける使用のための置換型１６，１７−環紋型ステロイド化合物
Document Type and Number:
Japanese Patent JP5658748
Kind Code:
B2
Abstract:
The present invention relates to substituted steroid compounds having the formula (I) Wherein R1 is H or halogen; R2 is H, (1C-4C)alkyl, (1C-4C)acyl, glucuronyl or sulfamoyl; R3 is H or halogen; R4 is H, (1C-4C)alkyl, (2C-4C)alkenyl or (2C-4C)alkynyl; R5 is methyl or ethyl; R6 is H or methyl; R7 is H or methyl; R8 is H or acyl for use in the treatment and prevention of endometriosis, for contraception, for hormonal therapy in perimenopausal and post-menopausal women, for the treatment of osteoporosis and for the treatment uterine fibroids and other menstrual-related disorders, such as dysfunctional uterine bleeding.
Inventors:
デイセカス，フレデリクス・アントニウス
ローゼン，ヒユベルト・ヤン・ヨゼフ
アツド，サミラ
エデルフエーン，アントニウス・ヘラルドウス・ヘンドリクス
ローゼン，ヒユベルト・ヤン・ヨゼフ
アツド，サミラ
エデルフエーン，アントニウス・ヘラルドウス・ヘンドリクス
Application Number:
JP2012514456A
Publication Date:
January 28, 2015
Filing Date:
June 09, 2010
Export Citation:
Assignee:
メルク・シャープ・エンド・ドーム・ベー・フェー
International Classes:
C07J53/00; A61K31/56; A61P15/00; A61P15/18
Attorney, Agent or Firm:
Iwase Yoshiwa
Makoto Ono
Yoshinori Kanayama
Michiaki Tsubokura
Kazuteru Shigemori
Kenji Ando
Yasufumi Shiroyama
Makoto Ono
Yoshinori Kanayama
Michiaki Tsubokura
Kazuteru Shigemori
Kenji Ando
Yasufumi Shiroyama