凝固カスケードの選択的抑制に有用な置換5員多環状化合物

Japanese Patent JP2005525413

A

The present invention relates to compounds, and prodrugs thereof, compositions and methods useful for preventing and treating thrombotic conditions in mammals. The compounds of the present invention, and prodrugs thereof, selectively inhibit certain proteases of the coagulation cascade.

South, Michael Es
Ronald Kay, Webber
Juan, Horn-Chi
Toss, Miharie Vui
Mooreman, Alan Yee
Jeffrey S. Snyder
Shorten, Jeffrey A.
Garland, Danny Jay
Rupel, Melvin El
Neumann, William Elle
Long, scott
Way fan
John the Trujillo
Parlow, John Jay
Dallin Yee, Jones
Case, blender
Hayes, Michael Jay

JP2004501381A

August 25, 2005

October 03, 2002

Click for automatic bibliography generation  

Pharmacia Corporation

A61K31/166; A61K31/341; A61K31/381; A61K31/40; A61K31/415; A61K31/4152; A61K31/4168; A61K31/4196; A61K31/421; A61K31/426; A61P7/02; A61P9/00; A61P11/00; A61P35/00; A61P43/00; C07C257/18; C07D207/14; C07D207/32; C07D207/34; C07D207/46; C07D211/56; C07D211/98; C07D213/74; C07D231/12; C07D231/38; C07D231/46; C07D231/48; C07D233/88; C07D237/04; C07D239/10; C07D239/22; C07D241/04; C07D241/20; C07D249/08; C07D249/14; C07D253/06; C07D253/075; C07D263/48; C07D265/02; C07D277/20; C07D277/42; C07D307/22; C07D333/36; C07D401/12; C07D403/10; C07D413/12; C07D471/04; (IPC1-7): C07C257/18; A61K31/166; A61K31/341; A61K31/381; A61K31/40; A61K31/415; A61K31/4152; A61K31/4168; A61K31/4196; A61K31/421; A61K31/426; A61P7/02; A61P9/00; A61P11/00; A61P35/00; A61P43/00; C07D207/14; C07D207/34; C07D231/12; C07D231/38; C07D231/46; C07D233/88; C07D249/14; C07D263/48; C07D277/20; C07D277/42; C07D307/22; C07D333/36

Kazuo Shamoto
Tadashi Masui
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Takako Koiso

Previous Patent: メラノコルチン受容体リガンド

Next Patent: 病原体ワクチン及びその使用方法