Title:
置換アリールおよびヘテロアリール誘導体、その製法および薬剤組成物としての使用
Document Type and Number:
Japanese Patent JP2005519994
Kind Code:
A
Abstract:
The invention relates to novel substituted aryl and heteroaryl derivatives of general formula (I), in which A, Ar, n, X, Y1, Y2, Y3, Y4, R1, and R5 are defined as per claim 1, to their prodrugs, tautomers, stereoisomers, mixtures and salts, in particular their physiologically compatible salts comprising inorganic or organic acids or bases, which have valuable characteristics. The compounds of the aforementioned formula (I), in which R5 contains no cyano group, have in particular an antithrombotic and a selective factor Xa inhibiting action with generally improved compatibility. The compounds of the aforementioned formula (I), in which R5 contains a cyano group constitute valuable intermediate products for producing the antithrombotic compounds of general formula (I).
More Like This:
| WO/2003/059873 | POTASSIUM CHANNEL MODULATORS |
| JP2003500384 | [Title of Invention] Factor Xa Inhibitor |
Inventors:
Prepke Henning
Lies Uwe
Naru Herbert
Stassen Jean-Marie
Wienen Wolfgang
Lies Uwe
Naru Herbert
Stassen Jean-Marie
Wienen Wolfgang
Application Number:
JP2004509636A
Publication Date:
July 07, 2005
Filing Date:
May 17, 2002
Export Citation:
Assignee:
Boehringer Ingelheim Pharma Gesellshaft Mitt Beschlenktel Haftung Und Company Comandito Gesellshaft
International Classes:
C07D295/16; A61K31/155; A61K31/166; A61K31/167; A61K31/18; A61K31/40; A61K31/4439; A61P7/02; A61P43/00; C07C257/18; C07C303/40; C07C311/37; C07D207/20; C07D213/38; C07D295/192; (IPC1-7): C07C257/18; A61K31/155; A61K31/166; A61K31/167; A61K31/18; A61K31/40; A61K31/4439; A61P7/02; A61P43/00; C07C303/40; C07C311/37; C07D207/20; C07D213/38; C07D295/16
Attorney, Agent or Firm:
Sadao Kumakura
Nobuo Ogawa
Atsushi Hakoda
Kenji Asai
Koji Hirayama
Nobuo Ogawa
Atsushi Hakoda
Kenji Asai
Koji Hirayama