Title:
Rafキナーゼインヒビターとしての置換ベンゾアゾールおよびその使用
Document Type and Number:
Japanese Patent JP4755991
Kind Code:
B2
Abstract:
New substituted benzazole compounds, compositions and methods of inhibition of Raf kinase activity in a human or animal subject are provided. The new compounds compositions may be used either alone or in combination with at least one additional agent for the treatment of a Raf kinase mediated disorder, such as cancer.
Inventors:
La Mercy, Savigli
Sabra Manian, Sharaddah
Joel, Barhagen
Poon, Daniel Jay.
Hansen, Teresa
Schaffer, Cynthia
McBride, Christopher
Levine, Barry H.
Costers, Ablanc
Ren Hoy, Paul A.
Sabra Manian, Sharaddah
Joel, Barhagen
Poon, Daniel Jay.
Hansen, Teresa
Schaffer, Cynthia
McBride, Christopher
Levine, Barry H.
Costers, Ablanc
Ren Hoy, Paul A.
Application Number:
JP2006535367A
Publication Date:
August 24, 2011
Filing Date:
October 15, 2004
Export Citation:
Assignee:
Novartis Bakushin's and Diagnostics, Incorporated
International Classes:
C07D401/12; A61K31/4439; A61K31/4745; A61K31/496; A61K31/506; C07D401/14; C07D405/14; C07D409/14; C07D413/12; C07D413/14; C07D417/12; C07D417/14; A61K31/122; A61K31/282; A61K31/4164; A61K31/444; A61K31/4545; A61K31/4709; A61K31/513; A61K31/519; A61K31/5377; A61K31/551; A61K31/675; A61K31/704; A61K31/7068; A61K33/24; A61P1/00; A61P1/16; A61P1/18; A61P5/00; A61P11/00; A61P13/08; A61P15/00; A61P17/00; A61P35/00; A61P35/02; A61P43/00
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita