Title:
選択的エストロゲン受容体分解剤としての置換ベンゾチオフェン類似体
Document Type and Number:
Japanese Patent JP7348665
Kind Code:
B2
Abstract:
In one aspect, the disclosure relates to relates to substituted benzothiophene analogs which are useful as selective degraders of estrogen receptor, methods of making same, pharmaceutical compositions comprising same, and methods of treating one or more clinical conditions associated with estrogen receptor, such as a cancer, including breast cancer, or osteoporosis. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.
Inventors:
Thatcher, Gregory Earle.
Sion, Louis
Zao, Thion
Ru, Yunlong
Gut Gesell, Lauren
Rosales, Carlo Ivan
Lee, Jan Feng
Sion, Louis
Zao, Thion
Ru, Yunlong
Gut Gesell, Lauren
Rosales, Carlo Ivan
Lee, Jan Feng
Application Number:
JP2020564048A
Publication Date:
September 21, 2023
Filing Date:
February 06, 2019
Export Citation:
Assignee:
THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS
International Classes:
C07D409/12; A61K31/138; A61K31/167; A61K31/277; A61K31/397; A61K31/4025; A61K31/4196; A61K31/4535; A61K31/565; A61K31/566; A61K31/57; A61K38/09; A61K39/395; A61K45/00; A61K51/00; A61P5/30; A61P35/00; A61P35/04; A61P43/00; C07D333/64
Domestic Patent References:
| JP2014503537A | ||||
| JP11511169A |
Foreign References:
| WO2016097071A1 | ||||
| WO2018148576A1 |
Attorney, Agent or Firm:
Patent Attorney Corporation Hiroe Associates Patent Office
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