Title:
異常な細胞増殖を特徴とする疾患を治療または予防するために有用な、置換ジフェニルインダノン、インダン、およびインドール化合物およびそれらの類縁体
Document Type and Number:
Japanese Patent JP4009062
Kind Code:
B2
Abstract:
The present invention provides substituted 3,3-diphenyl indanone, indane and indole compounds, as well as analogues thereof, which are specific, potent and safe inhibitors of mammalian cell proliferation. The compounds can be used to inhibit mammalian cell proliferation in situ as a therapeutic approach towards the treatment or prevention of diseases characterized by abnormal cell proliferation, such as cancer.
Inventors:
Brugnara, Carlo
Halperin, jose
Flakyger, Rudolph
Bellotto, Emile M. Jr.
Lombardy, Richard John
Clifford, John Jay
Gao, In Duo
Haider, Reem M
Kelleher, Awake
Musa, Adele M
Sakdeba, Yesp
Sun, Minhwa
Taft, Heather N
Halperin, jose
Flakyger, Rudolph
Bellotto, Emile M. Jr.
Lombardy, Richard John
Clifford, John Jay
Gao, In Duo
Haider, Reem M
Kelleher, Awake
Musa, Adele M
Sakdeba, Yesp
Sun, Minhwa
Taft, Heather N
Application Number:
JP2000521813A
Publication Date:
November 14, 2007
Filing Date:
November 20, 1998
Export Citation:
Assignee:
PRESIDENT & FELLOWS OF HARVARD COLLEGE
International Classes:
C07C13/465; A61K31/045; A61K31/075; A61K31/122; A61K31/15; A61K31/22; A61K31/275; A61K31/336; A61K31/357; A61K31/403; A61K31/404; A61P9/08; A61P9/10; A61P17/00; A61P35/00; C07C35/32; C07C43/18; C07C43/188; C07C43/192; C07C43/243; C07C43/247; C07C45/46; C07C45/68; C07C49/665; C07C49/697; C07C49/747; C07C69/157; C07C69/757; C07C69/76; C07C233/23; C07C233/32; C07C235/34; C07C235/78; C07C251/44; C07C255/33; C07C255/35; C07C255/36; C07C255/40; C07D209/40; C07D303/46; C07D317/20
Domestic Patent References:
| JP2001523717A | ||||
| JP2001521485A |
Attorney, Agent or Firm:
Kiyoji Kuzuwa