Title:
BRI-モジュレータとしての置換されたジスルホンアミド
Document Type and Number:
Japanese Patent JP2012507483
Kind Code:
A
Abstract:
Substituted disulfonamide compounds corresponding to formula I: In which R1, R2, R3, R4a, R4b, R5a, R5b, R8, R9a, R9b, R10, R11, a, b, s, t and A have defined meanings, pharmaceutical compositions containing one or more such compounds, processes for preparing such compounds, and a method of using such compounds for the treatment or inhibition of pain and/or other conditions mediated by the bradykinin receptor 1 (BR1).
Inventors:
Reich Melanie
Schunk Stephan
Yostock route
Hase Sabine
German Tino
Engels Michael Franz-Martin
Schunk Stephan
Yostock route
Hase Sabine
German Tino
Engels Michael Franz-Martin
Application Number:
JP2011533621A
Publication Date:
March 29, 2012
Filing Date:
November 04, 2009
Export Citation:
Assignee:
Grunenthal Gesellschaft Mito Beschlenktel Haftung
International Classes:
C07D207/08; A61K31/454; A61K31/496; A61P1/04; A61P3/04; A61P3/10; A61P9/00; A61P11/00; A61P17/00; A61P19/02; A61P25/00; A61P25/06; A61P29/00; A61P31/04; C07D401/12; C07D401/14; C07D409/14; C07D413/12; C07D451/06; C07D471/10; C07D487/10
Attorney, Agent or Firm:
Mitsufumi Esaki
Blacksmith
Katsunori Uenishi
Blacksmith
Katsunori Uenishi