Title:
キナーゼ阻害剤としての置換インダゾリル(インドリル)マレイミド誘導体
Document Type and Number:
Japanese Patent JP2007500748
Kind Code:
A
Abstract:
The present invention is directed to novel indazolyl-substituted pyrroline compounds of Formula (I): R2 is selected from the group consisting of -C1-8alkyl-Z, -C2-8alkenyl-Z and -C2-8alkynyl-Z; wherein the -C1-8alkyl-Z, -C2-8alkenyl-Z and -C2-8alkynyl-Z and Z is a 5 to 6 member aromatic monocyclic heteroaryl ring having from 2 to 4 heteroatoms. These compounds are useful as kinase or dual-kinase inhibitors, methods for producing such compounds and methods for treating or ameliorating a kinase or dual-kinase mediated disorder.
Inventors:
Twang, Han-Chiang
Marianov, Bruce Yee
Yes, Hong
Marianov, Bruce Yee
Yes, Hong
Application Number:
JP2006533550A
Publication Date:
January 18, 2007
Filing Date:
June 01, 2004
Export Citation:
Assignee:
JANSSEN PHARMACEUTICA NAAMLOZE VENNOOTSCHAP
International Classes:
C07D401/14; A61K31/416; A61K31/4178; A61K31/4192; A61K31/4439; A61P3/10; A61P7/02; A61P9/00; A61P9/04; A61P9/10; A61P9/12; A61P9/14; A61P11/06; A61P13/12; A61P17/02; A61P17/06; A61P17/14; A61P19/02; A61P25/00; A61P25/04; A61P25/08; A61P25/18; A61P25/24; A61P25/28; A61P27/02; A61P29/00; A61P31/18; A61P35/00; A61P35/02; A61P37/00; A61P37/02; A61P37/06; A61P43/00; C07D403/14
Attorney, Agent or Firm:
Heikichi Odashima